Category: 1416372-67-2

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 5-Fluoro-2-methylpyrimidin-4-amine, is researched, Molecular C5H6FN3, CAS is 1416372-67-2, about Synthesis of 4-amino-5-fluoropyrimidines and 5-amino-4-fluoropyrazoles from a β-fluoroenolate salt, the main research direction is amino fluoropyrimidine preparation; amidine hydrochloride potassium cyano fluoroethenolate cyclization; fluoropyrazole amino preparation; hydrazine potassium cyano fluoroethenolate cyclization; cyclization; fluorinated heterocycles; fluorine; pyrazoles; pyrimidines.Application of 1416372-67-2.

A synthesis of fluorinated pyrimidines I [R = H, OMe, Ph, etc.] under mild conditions from amidine hydrochlorides and potassium 2-cyano-2-fluoroethenolate was developed. A broad substrate scope was tested and mostly excellent yields were obtained. The synthesis of fluorinated aminopyrazoles from the same fluorinated precursor could be demonstrated but proceeded with lower efficiency.

Different reactions of this compound(5-Fluoro-2-methylpyrimidin-4-amine)Application of 1416372-67-2 require different conditions, so the reaction conditions are very important.

Reference:
Cinnoline – Wikipedia,
Cinnoline – an overview | ScienceDirect Topics

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Synthesis of 4-amino-5-fluoropyrimidines and 5-amino-4-fluoropyrazoles from a β-fluoroenolate salt, published in 2020, which mentions a compound: 1416372-67-2, Name is 5-Fluoro-2-methylpyrimidin-4-amine, Molecular C5H6FN3, Safety of 5-Fluoro-2-methylpyrimidin-4-amine.

A synthesis of fluorinated pyrimidines I [R = H, OMe, Ph, etc.] under mild conditions from amidine hydrochlorides and potassium 2-cyano-2-fluoroethenolate was developed. A broad substrate scope was tested and mostly excellent yields were obtained. The synthesis of fluorinated aminopyrazoles from the same fluorinated precursor could be demonstrated but proceeded with lower efficiency.

After consulting a lot of data, we found that this compound(1416372-67-2)Safety of 5-Fluoro-2-methylpyrimidin-4-amine can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Cinnoline – Wikipedia,
Cinnoline – an overview | ScienceDirect Topics

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Beilstein Journal of Organic Chemistry called Synthesis of 4-amino-5-fluoropyrimidines and 5-amino-4-fluoropyrazoles from a β-fluoroenolate salt, Author is Lucas, Tobias; Dietz, Jule-Philipp; Opatz, Till, which mentions a compound: 1416372-67-2, SMILESS is NC1=NC(C)=NC=C1F, Molecular C5H6FN3, Category: cinnoline.

A synthesis of fluorinated pyrimidines I [R = H, OMe, Ph, etc.] under mild conditions from amidine hydrochlorides and potassium 2-cyano-2-fluoroethenolate was developed. A broad substrate scope was tested and mostly excellent yields were obtained. The synthesis of fluorinated aminopyrazoles from the same fluorinated precursor could be demonstrated but proceeded with lower efficiency.

《Synthesis of 4-amino-5-fluoropyrimidines and 5-amino-4-fluoropyrazoles from a β-fluoroenolate salt》 provides a strategy for the preparation of materials with excellent comprehensive properties, which is conducive to broaden the application field of this compound(5-Fluoro-2-methylpyrimidin-4-amine)Category: cinnoline.

Reference:
Cinnoline – Wikipedia,
Cinnoline – an overview | ScienceDirect Topics

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 1416372-67-2, is researched, Molecular C5H6FN3, about Synthesis of 4-amino-5-fluoropyrimidines and 5-amino-4-fluoropyrazoles from a β-fluoroenolate salt, the main research direction is amino fluoropyrimidine preparation; amidine hydrochloride potassium cyano fluoroethenolate cyclization; fluoropyrazole amino preparation; hydrazine potassium cyano fluoroethenolate cyclization; cyclization; fluorinated heterocycles; fluorine; pyrazoles; pyrimidines.Quality Control of 5-Fluoro-2-methylpyrimidin-4-amine.

A synthesis of fluorinated pyrimidines I [R = H, OMe, Ph, etc.] under mild conditions from amidine hydrochlorides and potassium 2-cyano-2-fluoroethenolate was developed. A broad substrate scope was tested and mostly excellent yields were obtained. The synthesis of fluorinated aminopyrazoles from the same fluorinated precursor could be demonstrated but proceeded with lower efficiency.

After consulting a lot of data, we found that this compound(1416372-67-2)Quality Control of 5-Fluoro-2-methylpyrimidin-4-amine can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Cinnoline – Wikipedia,
Cinnoline – an overview | ScienceDirect Topics

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Beilstein Journal of Organic Chemistry called Synthesis of 4-amino-5-fluoropyrimidines and 5-amino-4-fluoropyrazoles from a β-fluoroenolate salt, Author is Lucas, Tobias; Dietz, Jule-Philipp; Opatz, Till, which mentions a compound: 1416372-67-2, SMILESS is NC1=NC(C)=NC=C1F, Molecular C5H6FN3, Quality Control of 5-Fluoro-2-methylpyrimidin-4-amine.

A synthesis of fluorinated pyrimidines I [R = H, OMe, Ph, etc.] under mild conditions from amidine hydrochlorides and potassium 2-cyano-2-fluoroethenolate was developed. A broad substrate scope was tested and mostly excellent yields were obtained. The synthesis of fluorinated aminopyrazoles from the same fluorinated precursor could be demonstrated but proceeded with lower efficiency.

After consulting a lot of data, we found that this compound(1416372-67-2)Quality Control of 5-Fluoro-2-methylpyrimidin-4-amine can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Cinnoline – Wikipedia,
Cinnoline – an overview | ScienceDirect Topics

The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 5-Fluoro-2-methylpyrimidin-4-amine( cas:1416372-67-2 ) is researched.Computed Properties of C5H6FN3.Lucas, Tobias; Dietz, Jule-Philipp; Opatz, Till published the article 《Synthesis of 4-amino-5-fluoropyrimidines and 5-amino-4-fluoropyrazoles from a β-fluoroenolate salt》 about this compound( cas:1416372-67-2 ) in Beilstein Journal of Organic Chemistry. Keywords: amino fluoropyrimidine preparation; amidine hydrochloride potassium cyano fluoroethenolate cyclization; fluoropyrazole amino preparation; hydrazine potassium cyano fluoroethenolate cyclization; cyclization; fluorinated heterocycles; fluorine; pyrazoles; pyrimidines. Let’s learn more about this compound (cas:1416372-67-2).

A synthesis of fluorinated pyrimidines I [R = H, OMe, Ph, etc.] under mild conditions from amidine hydrochlorides and potassium 2-cyano-2-fluoroethenolate was developed. A broad substrate scope was tested and mostly excellent yields were obtained. The synthesis of fluorinated aminopyrazoles from the same fluorinated precursor could be demonstrated but proceeded with lower efficiency.

After consulting a lot of data, we found that this compound(1416372-67-2)Computed Properties of C5H6FN3 can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Cinnoline – Wikipedia,
Cinnoline – an overview | ScienceDirect Topics

Application In Synthesis of 5-Fluoro-2-methylpyrimidin-4-amine. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: 5-Fluoro-2-methylpyrimidin-4-amine, is researched, Molecular C5H6FN3, CAS is 1416372-67-2, about Synthesis of 4-amino-5-fluoropyrimidines and 5-amino-4-fluoropyrazoles from a β-fluoroenolate salt.

A synthesis of fluorinated pyrimidines I [R = H, OMe, Ph, etc.] under mild conditions from amidine hydrochlorides and potassium 2-cyano-2-fluoroethenolate was developed. A broad substrate scope was tested and mostly excellent yields were obtained. The synthesis of fluorinated aminopyrazoles from the same fluorinated precursor could be demonstrated but proceeded with lower efficiency.

After consulting a lot of data, we found that this compound(1416372-67-2)Application In Synthesis of 5-Fluoro-2-methylpyrimidin-4-amine can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Cinnoline – Wikipedia,
Cinnoline – an overview | ScienceDirect Topics

The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 5-Fluoro-2-methylpyrimidin-4-amine( cas:1416372-67-2 ) is researched.Reference of 5-Fluoro-2-methylpyrimidin-4-amine.Lucas, Tobias; Dietz, Jule-Philipp; Opatz, Till published the article 《Synthesis of 4-amino-5-fluoropyrimidines and 5-amino-4-fluoropyrazoles from a β-fluoroenolate salt》 about this compound( cas:1416372-67-2 ) in Beilstein Journal of Organic Chemistry. Keywords: amino fluoropyrimidine preparation; amidine hydrochloride potassium cyano fluoroethenolate cyclization; fluoropyrazole amino preparation; hydrazine potassium cyano fluoroethenolate cyclization; cyclization; fluorinated heterocycles; fluorine; pyrazoles; pyrimidines. Let’s learn more about this compound (cas:1416372-67-2).

A synthesis of fluorinated pyrimidines I [R = H, OMe, Ph, etc.] under mild conditions from amidine hydrochlorides and potassium 2-cyano-2-fluoroethenolate was developed. A broad substrate scope was tested and mostly excellent yields were obtained. The synthesis of fluorinated aminopyrazoles from the same fluorinated precursor could be demonstrated but proceeded with lower efficiency.

This compound(5-Fluoro-2-methylpyrimidin-4-amine)Reference of 5-Fluoro-2-methylpyrimidin-4-amine was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.

Reference:
Cinnoline – Wikipedia,
Cinnoline – an overview | ScienceDirect Topics

The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 5-Fluoro-2-methylpyrimidin-4-amine( cas:1416372-67-2 ) is researched.Name: 5-Fluoro-2-methylpyrimidin-4-amine.Lucas, Tobias; Dietz, Jule-Philipp; Opatz, Till published the article 《Synthesis of 4-amino-5-fluoropyrimidines and 5-amino-4-fluoropyrazoles from a β-fluoroenolate salt》 about this compound( cas:1416372-67-2 ) in Beilstein Journal of Organic Chemistry. Keywords: amino fluoropyrimidine preparation; amidine hydrochloride potassium cyano fluoroethenolate cyclization; fluoropyrazole amino preparation; hydrazine potassium cyano fluoroethenolate cyclization; cyclization; fluorinated heterocycles; fluorine; pyrazoles; pyrimidines. Let’s learn more about this compound (cas:1416372-67-2).

A synthesis of fluorinated pyrimidines I [R = H, OMe, Ph, etc.] under mild conditions from amidine hydrochlorides and potassium 2-cyano-2-fluoroethenolate was developed. A broad substrate scope was tested and mostly excellent yields were obtained. The synthesis of fluorinated aminopyrazoles from the same fluorinated precursor could be demonstrated but proceeded with lower efficiency.

After consulting a lot of data, we found that this compound(1416372-67-2)Name: 5-Fluoro-2-methylpyrimidin-4-amine can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Cinnoline – Wikipedia,
Cinnoline – an overview | ScienceDirect Topics

Application of 1416372-67-2. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 5-Fluoro-2-methylpyrimidin-4-amine, is researched, Molecular C5H6FN3, CAS is 1416372-67-2, about Synthesis of 4-amino-5-fluoropyrimidines and 5-amino-4-fluoropyrazoles from a β-fluoroenolate salt. Author is Lucas, Tobias; Dietz, Jule-Philipp; Opatz, Till.

A synthesis of fluorinated pyrimidines I [R = H, OMe, Ph, etc.] under mild conditions from amidine hydrochlorides and potassium 2-cyano-2-fluoroethenolate was developed. A broad substrate scope was tested and mostly excellent yields were obtained. The synthesis of fluorinated aminopyrazoles from the same fluorinated precursor could be demonstrated but proceeded with lower efficiency.

This compound(5-Fluoro-2-methylpyrimidin-4-amine)Application of 1416372-67-2 was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.

Reference:
Cinnoline – Wikipedia,
Cinnoline – an overview | ScienceDirect Topics