In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Synthesis of 4-amino-5-fluoropyrimidines and 5-amino-4-fluoropyrazoles from a β-fluoroenolate salt, published in 2020, which mentions a compound: 1416372-67-2, Name is 5-Fluoro-2-methylpyrimidin-4-amine, Molecular C5H6FN3, Safety of 5-Fluoro-2-methylpyrimidin-4-amine.
A synthesis of fluorinated pyrimidines I [R = H, OMe, Ph, etc.] under mild conditions from amidine hydrochlorides and potassium 2-cyano-2-fluoroethenolate was developed. A broad substrate scope was tested and mostly excellent yields were obtained. The synthesis of fluorinated aminopyrazoles from the same fluorinated precursor could be demonstrated but proceeded with lower efficiency.
After consulting a lot of data, we found that this compound(1416372-67-2)Safety of 5-Fluoro-2-methylpyrimidin-4-amine can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Cinnoline – Wikipedia,
Cinnoline – an overview | ScienceDirect Topics