The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 2,3-Dihydrocinnolin-4(1H)-one hydrochloride(SMILESS: O=C1CNNC2=C1C=CC=C2.[H]Cl,cas:137195-33-6) is researched.Electric Literature of C34H22NO2P. The article 《Synthesis of new derivatives of [1,2,5]triazepino[1,2-a]cinnoline. I. Synthesis of 4-oxo-1,2,3,4-tetrahydrocinnoline hydrochlorides》 in relation to this compound, is published in Acta Poloniae Pharmaceutica. Let’s take a look at the latest research on this compound (cas:137195-33-6).
The title cinnolines (I, R1 = R3 = R4 = H, R2 = H, Cl, Me; R1 = R2 = R3 = H, R4 = Cl, Me, OMe; R1 = R4 = H, R2 = R3 = OMe; R2 = R3 = R4 = H, R1 = Cl) were prepared by reduction of appropriately substituted 4-hydroxycinnlines (70-80% yields) and 4-hydroxy-3-cinnolinecarboxylic acids (55-67% yields) with Zn dust in AcOH-EtOH.
After consulting a lot of data, we found that this compound(137195-33-6)Product Details of 137195-33-6 can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Cinnoline – Wikipedia,
Cinnoline – an overview | ScienceDirect Topics