Month: November 2023

Stanczak, A.; Kwapiszewski, W.; Szadowska, A.; Pakulska, W. published the article 《Synthesis and action on the central nervous system of some N2-substituted cinnoline derivatives》. Keywords: central nervous system cinnoline derivative preparation.They researched the compound: 2,3-Dihydrocinnolin-4(1H)-one hydrochloride( cas:137195-33-6 ).Computed Properties of C8H9ClN2O. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:137195-33-6) here.

Alkylation of 4-hydroxycinnolines using Et bromoacetate resulted in N2-substituted acetic acids. These acids were converted to esters and amides. Some of the obtained acids were reduced with zinc dust to give 4-oxo-1,2,3,4-tetrahydro-2-cinnolineacetic acids. Several of the compounds were tested for their effect on central nervous system.

After consulting a lot of data, we found that this compound(137195-33-6)Computed Properties of C8H9ClN2O can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Cinnoline – Wikipedia,
Cinnoline – an overview | ScienceDirect Topics

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 137195-33-6, is researched, Molecular C8H9ClN2O, about Synthesis and action on the central nervous system of some N2-substituted cinnoline derivatives, the main research direction is central nervous system cinnoline derivative preparation.Reference of 2,3-Dihydrocinnolin-4(1H)-one hydrochloride.

Alkylation of 4-hydroxycinnolines using Et bromoacetate resulted in N2-substituted acetic acids. These acids were converted to esters and amides. Some of the obtained acids were reduced with zinc dust to give 4-oxo-1,2,3,4-tetrahydro-2-cinnolineacetic acids. Several of the compounds were tested for their effect on central nervous system.

This compound(2,3-Dihydrocinnolin-4(1H)-one hydrochloride)Reference of 2,3-Dihydrocinnolin-4(1H)-one hydrochloride was discussed at the molecular level, the effects of temperature and reaction time on the properties of the compound were discussed, and the optimum reaction conditions were selected.

Reference:
Cinnoline – Wikipedia,
Cinnoline – an overview | ScienceDirect Topics