Kwapiszewski, Wincenty; Stanczak, Andrezej; Groszkowski, Stefan published an article about the compound: 2,3-Dihydrocinnolin-4(1H)-one hydrochloride( cas:137195-33-6,SMILESS:O=C1CNNC2=C1C=CC=C2.[H]Cl ).Related Products of 137195-33-6. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:137195-33-6) through the article.
Stirring 1,2,3,4-tetrahydrocinnolin-4-one (I) with BrCH2COCl (II) in H2O at 0° gave 76% III (X = Br, R = R1 = R2 = H). III (X = Cl, R1 = R2 = H; R = Cl, Me, MeO; R = R1 = H, R2 = Cl, Me; R = H, R1 = R2 = MeO) were prepared analogously in 49-74% yields from the appropriately substituted I and ClCH2COCl (IV). When I and II were refluxed 10 h in C6H6, diacetylation occurred to give 67% V (X = Br, R1 = R2 = H). V (X = Cl, R1 = R2 = MeO; R1 = H, R2 = Cl, Me) were prepared analogously. V (X = Cl, R1 = R2 = H) was obtained from the corresponding III and IV in the presence of Et3N. Refluxing I 10 h with ClCH2CH2COCl in C6H6 gave 54% VI, which was also obtained as a byproduct when a similar reaction was carried out at 0° in CHCl3; the main product (60% yield) was 2-(3-chloropropionyl)-1,2,3,4-tetrahydrocinnolin-4-one.
Although many compounds look similar to this compound(137195-33-6)Related Products of 137195-33-6, numerous studies have shown that this compound(SMILES:O=C1CNNC2=C1C=CC=C2.[H]Cl), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Cinnoline – Wikipedia,
Cinnoline – an overview | ScienceDirect Topics