Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 1416372-67-2, is researched, Molecular C5H6FN3, about Synthesis of 4-amino-5-fluoropyrimidines and 5-amino-4-fluoropyrazoles from a β-fluoroenolate salt, the main research direction is amino fluoropyrimidine preparation; amidine hydrochloride potassium cyano fluoroethenolate cyclization; fluoropyrazole amino preparation; hydrazine potassium cyano fluoroethenolate cyclization; cyclization; fluorinated heterocycles; fluorine; pyrazoles; pyrimidines.Name: 5-Fluoro-2-methylpyrimidin-4-amine.
A synthesis of fluorinated pyrimidines I [R = H, OMe, Ph, etc.] under mild conditions from amidine hydrochlorides and potassium 2-cyano-2-fluoroethenolate was developed. A broad substrate scope was tested and mostly excellent yields were obtained. The synthesis of fluorinated aminopyrazoles from the same fluorinated precursor could be demonstrated but proceeded with lower efficiency.
In addition to the literature in the link below, there is a lot of literature about this compound(5-Fluoro-2-methylpyrimidin-4-amine)Name: 5-Fluoro-2-methylpyrimidin-4-amine, illustrating the importance and wide applicability of this compound(1416372-67-2).
Reference:
Cinnoline – Wikipedia,
Cinnoline – an overview | ScienceDirect Topics