Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 137195-33-6, is researched, SMILESS is O=C1CNNC2=C1C=CC=C2.[H]Cl, Molecular C8H9ClN2OJournal, Acta Poloniae Pharmaceutica called Synthesis of new derivatives of [1,2,5]triazepino[1,2-a]cinnoline. I. Synthesis of 4-oxo-1,2,3,4-tetrahydrocinnoline hydrochlorides, Author is Groszkowski, Stefan; Stanczak, Andrzej, the main research direction is oxotetrahydrocinnoline hydrochloride; cinnoline oxotetrahydro.Safety of 2,3-Dihydrocinnolin-4(1H)-one hydrochloride.
The title cinnolines (I, R1 = R3 = R4 = H, R2 = H, Cl, Me; R1 = R2 = R3 = H, R4 = Cl, Me, OMe; R1 = R4 = H, R2 = R3 = OMe; R2 = R3 = R4 = H, R1 = Cl) were prepared by reduction of appropriately substituted 4-hydroxycinnlines (70-80% yields) and 4-hydroxy-3-cinnolinecarboxylic acids (55-67% yields) with Zn dust in AcOH-EtOH.
There is still a lot of research devoted to this compound(SMILES：O=C1CNNC2=C1C=CC=C2.[H]Cl)Safety of 2,3-Dihydrocinnolin-4(1H)-one hydrochloride, and with the development of science, more effects of this compound(137195-33-6) can be discovered.
Reference:
Cinnoline – Wikipedia,
Cinnoline – an overview | ScienceDirect Topics