A small discovery about 1416372-67-2

If you want to learn more about this compound(5-Fluoro-2-methylpyrimidin-4-amine)Related Products of 1416372-67-2, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(1416372-67-2).

Related Products of 1416372-67-2. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 5-Fluoro-2-methylpyrimidin-4-amine, is researched, Molecular C5H6FN3, CAS is 1416372-67-2, about Synthesis of 4-amino-5-fluoropyrimidines and 5-amino-4-fluoropyrazoles from a β-fluoroenolate salt. Author is Lucas, Tobias; Dietz, Jule-Philipp; Opatz, Till.

A synthesis of fluorinated pyrimidines I [R = H, OMe, Ph, etc.] under mild conditions from amidine hydrochlorides and potassium 2-cyano-2-fluoroethenolate was developed. A broad substrate scope was tested and mostly excellent yields were obtained. The synthesis of fluorinated aminopyrazoles from the same fluorinated precursor could be demonstrated but proceeded with lower efficiency.

If you want to learn more about this compound(5-Fluoro-2-methylpyrimidin-4-amine)Related Products of 1416372-67-2, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(1416372-67-2).

Reference:
Cinnoline – Wikipedia,
Cinnoline – an overview | ScienceDirect Topics